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Vascularization of primary and secondary ossification centres in the human growth plate

Overview of attention for article published in BMC Developmental Biology, August 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#46 of 369)
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

blogs
1 blog
twitter
1 X user

Citations

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27 Dimensions

Readers on

mendeley
53 Mendeley
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Title
Vascularization of primary and secondary ossification centres in the human growth plate
Published in
BMC Developmental Biology, August 2014
DOI 10.1186/s12861-014-0036-7
Pubmed ID
Authors

Sonja M Walzer, Erdal Cetin, Ruth Grübl-Barabas, Irene Sulzbacher, Beate Rueger, Werner Girsch, Stefan Toegel, Reinhard Windhager, Michael B Fischer

Abstract

The switch from cartilage template to bone during endochondral ossification of the growth plate requires a dynamic and close interaction between cartilage and the developing vasculature. Vascular invasion of the primarily avascular hypertrophic chondrocyte zone brings chondroclasts, osteoblast- and endothelial precursor cells into future centres of ossification.Vascularization of human growth plates of polydactylic digits was studied by immunohistochemistry, confocal-laser-scanning-microscopy and RT-qPCR using markers specific for endothelial cells CD34 and CD31, smooth muscle cells α-SMA, endothelial progenitor cells CD133, CXCR4, VEGFR-2 and mesenchymal progenitor cells CD90 and CD105. In addition, morphometric analysis was performed to quantify RUNX2+ and DLX5+ hypertrophic chondrocytes, RANK+ chondro- and osteoclasts, and CD133+ progenitors in different zones of the growth plate.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Austria 1 2%
Unknown 50 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 17%
Researcher 9 17%
Student > Master 7 13%
Student > Bachelor 6 11%
Other 4 8%
Other 10 19%
Unknown 8 15%
Readers by discipline Count As %
Medicine and Dentistry 14 26%
Biochemistry, Genetics and Molecular Biology 8 15%
Agricultural and Biological Sciences 8 15%
Engineering 3 6%
Computer Science 1 2%
Other 6 11%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2015.
All research outputs
#3,662,144
of 22,765,347 outputs
Outputs from BMC Developmental Biology
#46
of 369 outputs
Outputs of similar age
#38,022
of 236,621 outputs
Outputs of similar age from BMC Developmental Biology
#3
of 7 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 369 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,621 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.