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Pioglitazone modulates the proliferation and apoptosis of vascular smooth muscle cells via peroxisome proliferators-activated receptor-gamma

Overview of attention for article published in Diabetology & Metabolic Syndrome, September 2014
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2 tweeters

Citations

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6 Mendeley
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Title
Pioglitazone modulates the proliferation and apoptosis of vascular smooth muscle cells via peroxisome proliferators-activated receptor-gamma
Published in
Diabetology & Metabolic Syndrome, September 2014
DOI 10.1186/1758-5996-6-101
Pubmed ID
Authors

Jing Wan, Zhichao Xiao, Shengping Chao, Shixi Xiong, Xuedong Gan, Xuguang Qiu, Chang Xu, Yexin Ma, Xin Tu

Abstract

PPARγ is a member of the nuclear hormone receptor superfamily. It has been considered as a mediator regulating metabolism, anti-inflammation, and pro-proliferation in the Vascular Smooth Muscle Cells (VSMCs). Thiazolidinediones (TZDs), synthetic ligands of PPARγ, have anti-proliferative and pro-apoptotic effects on VSMCs, which prevent the formation and progression of atherosclerosis and restenosis following percutaneous coronary intervention (PCI). However, the underlying mechanism remains elusive. This present study therefore aimed to investigate the signaling pathway by which pioglitazone, one of TZDs, inhibits proliferation and induces apoptosis of VSMCs.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 6 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 2 33%
Student > Ph. D. Student 1 17%
Student > Postgraduate 1 17%
Student > Master 1 17%
Unknown 1 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 50%
Pharmacology, Toxicology and Pharmaceutical Science 2 33%
Unknown 1 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2022.
All research outputs
#17,364,138
of 22,261,010 outputs
Outputs from Diabetology & Metabolic Syndrome
#416
of 641 outputs
Outputs of similar age
#152,237
of 227,708 outputs
Outputs of similar age from Diabetology & Metabolic Syndrome
#1
of 1 outputs
Altmetric has tracked 22,261,010 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 641 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,708 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them