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EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer

Overview of attention for article published in Molecular Cancer, October 2014
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  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
2 tweeters

Citations

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19 Dimensions

Readers on

mendeley
29 Mendeley
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Title
EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer
Published in
Molecular Cancer, October 2014
DOI 10.1186/1476-4598-13-233
Pubmed ID
Authors

Xiaofeng Lin, Shuangshuang Zhong, Xiaofeng Ye, Yueling Liao, Feng Yao, Xiaohua Yang, Beibei Sun, Jie Zhang, Qi Li, Yong Gao, Yifan Wang, Jingyi Liu, Baohui Han, Y Eugene Chin, Binhua P Zhou, Jiong Deng

Abstract

GPRC5A is a retinoic acid inducible gene that is preferentially expressed in lung tissue. Gprc5a- knockout mice develop spontaneous lung cancer, indicating Gprc5a is a lung tumor suppressor gene. GPRC5A expression is frequently suppressed in majority of non-small cell lung cancers (NSCLCs), however, elevated GPRC5A is still observed in a small portion of NSCLC cell lines and tumors, suggesting that the tumor suppressive function of GPRC5A is inhibited in these tumors by an unknown mechanism.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 24%
Student > Postgraduate 4 14%
Professor 3 10%
Researcher 3 10%
Student > Master 2 7%
Other 3 10%
Unknown 7 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 41%
Medicine and Dentistry 6 21%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Environmental Science 1 3%
Agricultural and Biological Sciences 1 3%
Other 1 3%
Unknown 7 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2014.
All research outputs
#14,312,396
of 21,321,698 outputs
Outputs from Molecular Cancer
#966
of 1,611 outputs
Outputs of similar age
#128,634
of 226,701 outputs
Outputs of similar age from Molecular Cancer
#1
of 1 outputs
Altmetric has tracked 21,321,698 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,611 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,701 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them