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EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer

Overview of attention for article published in Molecular Cancer, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

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2 X users
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2 patents

Citations

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25 Dimensions

Readers on

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46 Mendeley
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Title
EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer
Published in
Molecular Cancer, October 2014
DOI 10.1186/1476-4598-13-233
Pubmed ID
Authors

Xiaofeng Lin, Shuangshuang Zhong, Xiaofeng Ye, Yueling Liao, Feng Yao, Xiaohua Yang, Beibei Sun, Jie Zhang, Qi Li, Yong Gao, Yifan Wang, Jingyi Liu, Baohui Han, Y Eugene Chin, Binhua P Zhou, Jiong Deng

Abstract

GPRC5A is a retinoic acid inducible gene that is preferentially expressed in lung tissue. Gprc5a- knockout mice develop spontaneous lung cancer, indicating Gprc5a is a lung tumor suppressor gene. GPRC5A expression is frequently suppressed in majority of non-small cell lung cancers (NSCLCs), however, elevated GPRC5A is still observed in a small portion of NSCLC cell lines and tumors, suggesting that the tumor suppressive function of GPRC5A is inhibited in these tumors by an unknown mechanism.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 22%
Unspecified 4 9%
Researcher 4 9%
Student > Postgraduate 4 9%
Student > Master 4 9%
Other 7 15%
Unknown 13 28%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 33%
Medicine and Dentistry 7 15%
Unspecified 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Agricultural and Biological Sciences 1 2%
Other 5 11%
Unknown 13 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 November 2023.
All research outputs
#4,717,867
of 24,946,857 outputs
Outputs from Molecular Cancer
#374
of 1,876 outputs
Outputs of similar age
#49,241
of 261,801 outputs
Outputs of similar age from Molecular Cancer
#4
of 39 outputs
Altmetric has tracked 24,946,857 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,876 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,801 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.