A curated C. difficile strain 630 metabolic network: prediction of essential targets and inhibitors

Overview of attention for article published in BMC Systems Biology, October 2014

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In the top 25% of all research outputs scored by Altmetric
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@PriceLab_ISB @BenHeavner @ISBNathanPrice gaps/dead-ends/generic metabolites - only work with FBA because of 0 flux http://t.co/nwso9p90KB

.@gepasi @neilswainston @SAnaniadou @dbkell I Auto validation also useful but data hidden in old lit. We did by hand http://t.co/nwso9p90KB

院内感染の主要な原因であるクロストリジウム・ディフィシル病原性株630において、広範囲にキュレーションされた代謝ネットワークを構築した。76必須遺伝子と39必須遺伝子対の存在が予測され、新たな抗生物質開発への貢献が期待できる。 http://t.co/tZ9i2Q1hJ2 SK

C. difficile metabolic network points to existing drugs with potential for drug repositioning http://t.co/ZeELFgEdYo

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