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Mendeley readers
Attention Score in Context
| Title |
The impact of type 2 diabetes on bone metabolism
|
|---|---|
| Published in |
Diabetology & Metabolic Syndrome, October 2017
|
| DOI | 10.1186/s13098-017-0278-1 |
| Pubmed ID | |
| Authors |
Claudia Pinheiro Sanches, Andre Gustavo Daher Vianna, Fellype de Carvalho Barreto |
| Abstract |
Diabetes complications and osteoporotic fractures are two of the most important causes of morbidity and mortality in older patients and share many features including genetic susceptibility, molecular mechanisms, and environmental factors. Type 2 diabetes mellitus (T2DM) compromises bone microarchitecture by inducing abnormal bone cell function and matrix structure, with increased osteoblast apoptosis, diminished osteoblast differentiation, and enhanced osteoclast-mediated bone resorption. The linkage between these two chronic diseases creates a possibility that certain antidiabetic therapies may affect bone quality. Both glycemic and bone homeostasis are under control of common regulatory factors. These factors include insulin, accumulation of advanced glycation end products, peroxisome proliferator-activated receptor gamma, gastrointestinal hormones (such as the glucose-dependent insulinotropic peptide and the glucagon-like peptides 1 and 2), and bone-derived hormone osteocalcin. This background allows individual pharmacological targets for antidiabetic therapies to affect the bone quality due to their indirect effects on bone cell differentiation and bone remodeling process. Moreover, it's important to consider the fragility fractures as another diabetes complication and discuss more deeply about the requirement for adequate screening and preventive measures. This review aims to briefly explore the impact of T2DM on bone metabolic and mechanical proprieties and fracture risk. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 50% |
| Colombia | 1 | 25% |
| Japan | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 117 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 20% |
| Student > Master | 19 | 16% |
| Student > Bachelor | 13 | 11% |
| Researcher | 8 | 7% |
| Lecturer | 8 | 7% |
| Other | 17 | 15% |
| Unknown | 29 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 24% |
| Biochemistry, Genetics and Molecular Biology | 19 | 16% |
| Engineering | 6 | 5% |
| Materials Science | 5 | 4% |
| Agricultural and Biological Sciences | 4 | 3% |
| Other | 19 | 16% |
| Unknown | 36 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2017.
All research outputs
#13,496,757
of 23,006,268 outputs
Outputs from Diabetology & Metabolic Syndrome
#282
of 675 outputs
Outputs of similar age
#163,860
of 327,202 outputs
Outputs of similar age from Diabetology & Metabolic Syndrome
#6
of 11 outputs
Altmetric has tracked 23,006,268 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 675 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,202 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.