Title |
Leveraging transcription factors to speed cellobiose fermentation by Saccharomyces cerevisiae
|
---|---|
Published in |
Biotechnology for Biofuels and Bioproducts, August 2014
|
DOI | 10.1186/s13068-014-0126-6 |
Pubmed ID | |
Authors |
Yuping Lin, Kulika Chomvong, Ligia Acosta-Sampson, Raíssa Estrela, Jonathan M Galazka, Soo Rin Kim, Yong-Su Jin, Jamie HD Cate |
Abstract |
Saccharomyces cerevisiae, a key organism used for the manufacture of renewable fuels and chemicals, has been engineered to utilize non-native sugars derived from plant cell walls, such as cellobiose and xylose. However, the rates and efficiencies of these non-native sugar fermentations pale in comparison with those of glucose. Systems biology methods, used to understand biological networks, hold promise for rational microbial strain development in metabolic engineering. Here, we present a systematic strategy for optimizing non-native sugar fermentation by recombinant S. cerevisiae, using cellobiose as a model. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 67% |
France | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 2% |
United States | 1 | 2% |
France | 1 | 2% |
Unknown | 59 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 14 | 23% |
Researcher | 13 | 21% |
Student > Bachelor | 5 | 8% |
Student > Master | 5 | 8% |
Student > Doctoral Student | 4 | 6% |
Other | 10 | 16% |
Unknown | 11 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 31 | 50% |
Biochemistry, Genetics and Molecular Biology | 12 | 19% |
Engineering | 3 | 5% |
Medicine and Dentistry | 1 | 2% |
Business, Management and Accounting | 1 | 2% |
Other | 0 | 0% |
Unknown | 14 | 23% |