@MaTeFerretti @AlbertoEspay ApoE4 is generally associated with lower CSF Aβ42 (https://t.co/JYuOknmJgW & https://t.co/NqhUWbVZLu), while ApoE2 is associated with high CSF Aβ42 & protection. Pathogenesis seems much more dependent on LOF than GOF, mo
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Open Access UCL Research: Preclinical effects of APOE epsilon 4 on cerebrospinal fluid A beta 42 concentrations https://t.co/K6Aa02rJ38
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IoN UCL PubMed: Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations. https://t.co/kBXCNvLNro
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Preclinical effects of APOE4 on cerebrospinal fluid A-beta42 concentrations https://t.co/Xt0b6Sn4Kw #Alzheimers 7yr diff between genotypes