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X Demographics
Mendeley readers
| Title |
Lipid metabolism fattens up hedgehog signaling
|
|---|---|
| Published in |
BMC Biology, October 2017
|
| DOI | 10.1186/s12915-017-0442-y |
| Pubmed ID | |
| Authors |
Robert Blassberg, John Jacob |
| Abstract |
Signaling pathways direct organogenesis, often through concentration-dependent effects on cells. The hedgehog pathway enables cells to sense and respond to hedgehog ligands, of which the best studied is sonic hedgehog. Hedgehog signaling is essential for development, proliferation, and stem cell maintenance, and it is a driver of certain cancers. Lipid metabolism has a profound influence on both hedgehog signal transduction and the properties of the ligands themselves, leading to changes in the strength of hedgehog signaling and cellular functions. Here we review the evolving understanding of the relationship between lipids and hedgehog signaling. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 14% |
| Australia | 1 | 14% |
| United Kingdom | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 3 | 43% |
| Members of the public | 2 | 29% |
| Science communicators (journalists, bloggers, editors) | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 77 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 19% |
| Student > Ph. D. Student | 8 | 10% |
| Student > Master | 7 | 9% |
| Student > Doctoral Student | 6 | 8% |
| Professor > Associate Professor | 5 | 6% |
| Other | 12 | 16% |
| Unknown | 24 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 20 | 26% |
| Agricultural and Biological Sciences | 11 | 14% |
| Neuroscience | 7 | 9% |
| Medicine and Dentistry | 3 | 4% |
| Immunology and Microbiology | 2 | 3% |
| Other | 6 | 8% |
| Unknown | 28 | 36% |