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Normal weight diabetic patients versus obese diabetics: relation of overall and abdominal adiposity to vascular health

Overview of attention for article published in Cardiovascular Diabetology, October 2014
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Title
Normal weight diabetic patients versus obese diabetics: relation of overall and abdominal adiposity to vascular health
Published in
Cardiovascular Diabetology, October 2014
DOI 10.1186/s12933-014-0141-8
Pubmed ID
Authors

Alla Lukich, Dov Gavish, Marina Shargorodsky

Abstract

ObjectiveThe present study investigated the impact of overall obesity defined by BMI and abdominal obesity defined by WC on vascular atherosclerotic changes in obese and normal weight diabetic subjects.Design and methods285 subjects were divided according to presence diabetes mellitus (DM) and obesity: Group 1 included 144 nonobese subjects without DM; Group 2 consisted of 141 type 2 diabetic patients. Then diabetic patients were divided into two groups according to presence of overall obesity, defined by BMI and furthermore, abdominal obesity, defined by waist circumference (WC). Pulse wave velocity (PWV) and augmentation index (AI) were performed using SphygmoCor (version 7.1, AtCor Medical, Sydney, Australia).Results Between Group Comparisons by BMI: Diabetic subjects with and without overall obesity did not differ from one another in terms of AI and PWV. Between Group Comparisons by WC: AI as well as PWV increased consistently from Group 1 to Group 3, AI and PWV were significantly higher in abdominally obese diabetic subjects than in the diabetics without abdominal obesity (p¿=¿0.008 and p¿=¿0.013, respectively). Significant by-group differences in PWV and AI persisted after adjustment for age, sex, blood pressure, fasting glucose and BMI.ConclusionsAbdominal obesity defined by WC was associated with significantly higher AI and PWV in in both diabetic men and women; whereas overall obesity defined by BMI did not predict adverse vascular changes in this study population. Abdominal obesity was associated with an adverse effect on blood vessels, independently of age, sex, blood pressure, fasting glucose and BMI.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 19%
Student > Postgraduate 6 14%
Student > Master 4 9%
Student > Ph. D. Student 3 7%
Student > Bachelor 3 7%
Other 6 14%
Unknown 13 30%
Readers by discipline Count As %
Medicine and Dentistry 20 47%
Chemical Engineering 1 2%
Biochemistry, Genetics and Molecular Biology 1 2%
Mathematics 1 2%
Philosophy 1 2%
Other 4 9%
Unknown 15 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2015.
All research outputs
#20,241,019
of 22,768,097 outputs
Outputs from Cardiovascular Diabetology
#1,209
of 1,374 outputs
Outputs of similar age
#217,075
of 260,345 outputs
Outputs of similar age from Cardiovascular Diabetology
#13
of 14 outputs
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We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.