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Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

Overview of attention for article published in Alzheimer's Research & Therapy, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

news
1 news outlet
twitter
1 tweeter

Citations

dimensions_citation
83 Dimensions

Readers on

mendeley
137 Mendeley
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Title
Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels
Published in
Alzheimer's Research & Therapy, January 2014
DOI 10.1186/alzrt268
Pubmed ID
Authors

Mariet Allen, Michaela Kachadoorian, Zachary Quicksall, Fanggeng Zou, High Chai, Curtis Younkin, Julia E Crook, V Pankratz, Minerva M Carrasquillo, Siddharth Krishnan, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Gina Bisceglio, Christopher P Kolbert, Jin Jen, Shubhabrata Mukherjee, John K Kauwe, Paul K Crane, Jonathan L Haines, Richard Mayeux, Margaret A Pericak-Vance, Lindsay A Farrer, Gerard D Schellenberg, Joseph E Parisi, Ronald C Petersen, Neill R Graff-Radford, Dennis W Dickson, Steven G Younkin, Nilüfer Ertekin-Taner

Abstract

MAPT encodes for tau, the predominant component of neurofibrillary tangles that are neuropathological hallmarks of Alzheimer's disease (AD). Genetic association of MAPT variants with late-onset AD (LOAD) risk has been inconsistent, although insufficient power and incomplete assessment of MAPT haplotypes may account for this.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 1%
United States 2 1%
Germany 1 <1%
Unknown 132 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 28 20%
Researcher 26 19%
Student > Bachelor 18 13%
Student > Master 13 9%
Other 9 7%
Other 16 12%
Unknown 27 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 29 21%
Agricultural and Biological Sciences 29 21%
Neuroscience 21 15%
Medicine and Dentistry 7 5%
Computer Science 3 2%
Other 14 10%
Unknown 34 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2016.
All research outputs
#1,419,231
of 12,561,272 outputs
Outputs from Alzheimer's Research & Therapy
#266
of 539 outputs
Outputs of similar age
#30,559
of 229,000 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#8
of 19 outputs
Altmetric has tracked 12,561,272 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 539 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.0. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,000 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.