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scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing

Overview of attention for article published in Genome Biology, October 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
41 X users

Citations

dimensions_citation
79 Dimensions

Readers on

mendeley
210 Mendeley
citeulike
1 CiteULike
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Title
scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing
Published in
Genome Biology, October 2017
DOI 10.1186/s13059-017-1340-x
Pubmed ID
Authors

Gal Avital, Roi Avraham, Amy Fan, Tamar Hashimshony, Deborah T. Hung, Itai Yanai

Abstract

The interaction between a pathogen and a host is a highly dynamic process in which both agents activate complex programs. Here, we introduce a single-cell RNA-sequencing method, scDual-Seq, that simultaneously captures both host and pathogen transcriptomes. We use it to study the process of infection of individual mouse macrophages with the intracellular pathogen Salmonella typhimurium. Among the infected macrophages, we find three subpopulations and we show evidence for a linear progression through these subpopulations, supporting a model in which these three states correspond to consecutive stages of infection.

X Demographics

X Demographics

The data shown below were collected from the profiles of 41 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 210 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 210 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 56 27%
Researcher 38 18%
Student > Master 16 8%
Student > Doctoral Student 15 7%
Student > Bachelor 13 6%
Other 19 9%
Unknown 53 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 54 26%
Agricultural and Biological Sciences 34 16%
Immunology and Microbiology 33 16%
Medicine and Dentistry 10 5%
Engineering 6 3%
Other 15 7%
Unknown 58 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2022.
All research outputs
#1,046,575
of 25,382,440 outputs
Outputs from Genome Biology
#753
of 4,468 outputs
Outputs of similar age
#21,816
of 339,185 outputs
Outputs of similar age from Genome Biology
#24
of 60 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,468 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,185 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.