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The C. elegans dosage compensation complex mediates interphase X chromosome compaction

Overview of attention for article published in Epigenetics & Chromatin, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Average Attention Score compared to outputs of the same age and source

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11 X users

Citations

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Title
The C. elegans dosage compensation complex mediates interphase X chromosome compaction
Published in
Epigenetics & Chromatin, October 2014
DOI 10.1186/1756-8935-7-31
Pubmed ID
Authors

Alyssa C Lau, Kentaro Nabeshima, Györgyi Csankovszki

Abstract

Dosage compensation is a specialized gene regulatory mechanism which equalizes X-linked gene expression between sexes. In Caenorhabditis elegans, dosage compensation is achieved by the activity of the dosage compensation complex (DCC). The DCC localizes to both X chromosomes in hermaphrodites to downregulate gene expression by half. The DCC contains a subcomplex (condensin I(DC)) similar to the evolutionarily conserved condensin complexes which play fundamental roles in chromosome dynamics during mitosis and meiosis. Therefore, mechanisms related to mitotic chromosome condensation have been long hypothesized to mediate dosage compensation. However experimental evidence was lacking.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 2%
Switzerland 1 2%
Unknown 58 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 23%
Student > Bachelor 12 20%
Student > Master 9 15%
Researcher 5 8%
Student > Doctoral Student 4 7%
Other 7 12%
Unknown 9 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 42%
Agricultural and Biological Sciences 17 28%
Neuroscience 2 3%
Physics and Astronomy 1 2%
Psychology 1 2%
Other 2 3%
Unknown 12 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2014.
All research outputs
#5,695,708
of 23,539,593 outputs
Outputs from Epigenetics & Chromatin
#209
of 574 outputs
Outputs of similar age
#60,569
of 261,910 outputs
Outputs of similar age from Epigenetics & Chromatin
#7
of 12 outputs
Altmetric has tracked 23,539,593 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 574 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 261,910 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.