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pEPito: a significantly improved non-viral episomal expression vector for mammalian cells

Overview of attention for article published in BMC Biotechnology, March 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

twitter
1 tweeter
patent
1 patent
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
52 Dimensions

Readers on

mendeley
122 Mendeley
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Title
pEPito: a significantly improved non-viral episomal expression vector for mammalian cells
Published in
BMC Biotechnology, March 2010
DOI 10.1186/1472-6750-10-20
Pubmed ID
Authors

Rudolf Haase, Orestis Argyros, Suet-Ping Wong, Richard P Harbottle, Hans J Lipps, Manfred Ogris, Terese Magnusson, Maria G Vizoso Pinto, Jürgen Haas, Armin Baiker

Abstract

The episomal replication of the prototype vector pEPI-1 depends on a transcription unit starting from the constitutively expressed Cytomegalovirus immediate early promoter (CMV-IEP) and directed into a 2000 bp long matrix attachment region sequence (MARS) derived from the human beta-interferon gene. The original pEPI-1 vector contains two mammalian transcription units and a total of 305 CpG islands, which are located predominantly within the vector elements necessary for bacterial propagation and known to be counterproductive for persistent long-term transgene expression.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 2%
Netherlands 1 <1%
Norway 1 <1%
Unknown 118 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 24%
Student > Ph. D. Student 25 20%
Student > Master 17 14%
Other 10 8%
Professor > Associate Professor 8 7%
Other 22 18%
Unknown 11 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 54 44%
Biochemistry, Genetics and Molecular Biology 33 27%
Medicine and Dentistry 7 6%
Engineering 4 3%
Immunology and Microbiology 3 2%
Other 10 8%
Unknown 11 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2022.
All research outputs
#4,069,103
of 20,947,122 outputs
Outputs from BMC Biotechnology
#230
of 909 outputs
Outputs of similar age
#50,631
of 252,384 outputs
Outputs of similar age from BMC Biotechnology
#39
of 92 outputs
Altmetric has tracked 20,947,122 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 909 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 252,384 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.