Title |
Risky monetary behavior in chronic back pain is associated with altered modular connectivity of the nucleus accumbens
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Published in |
BMC Research Notes, October 2014
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DOI | 10.1186/1756-0500-7-739 |
Pubmed ID | |
Authors |
Sara E Berger, Alexis T Baria, Marwan N Baliki, Ali Mansour, Kristi M Herrmann, Souraya Torbey, Lejian Huang, Elle L Parks, Thomas J Schnizter, A Vania Apkarian |
Abstract |
The nucleus accumbens (NAc) has a well established role in reward processing. Yet, there is growing evidence showing that NAc function, and its connections to other parts of the brain, is also critically involved in the emergence of chronic back pain (CBP). Pain patients are known to perform abnormally in reward-related tasks, which suggests an intriguing link between pain, NAc connectivity, and reward behavior. In the present study, we compared performance on a gambling task (indicating willingness to risk losing money) between healthy pain-free controls (CON) and individuals with CBP. We then measured modular connectivity of each participants' NAc with resting state functional MRI to investigate how connectivity accounts for reward behavior in the presence and absence of pain. |
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United States | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
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Members of the public | 4 | 80% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
Geographical breakdown
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France | 1 | <1% |
Australia | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 103 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 21 | 20% |
Researcher | 19 | 18% |
Professor > Associate Professor | 10 | 9% |
Student > Master | 8 | 8% |
Student > Bachelor | 8 | 8% |
Other | 25 | 24% |
Unknown | 15 | 14% |
Readers by discipline | Count | As % |
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Neuroscience | 21 | 20% |
Psychology | 18 | 17% |
Medicine and Dentistry | 15 | 14% |
Agricultural and Biological Sciences | 6 | 6% |
Nursing and Health Professions | 5 | 5% |
Other | 12 | 11% |
Unknown | 29 | 27% |