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O-GlcNAc modification is associated with insulin sensitivity in the whole blood of healthy young adult males

Overview of attention for article published in Diabetology & Metabolic Syndrome, September 2014
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Title
O-GlcNAc modification is associated with insulin sensitivity in the whole blood of healthy young adult males
Published in
Diabetology & Metabolic Syndrome, September 2014
DOI 10.1186/1758-5996-6-96
Pubmed ID
Authors

Jason P Myslicki, Jane Shearer, Dustin S Hittel, Curtis C Hughey, Darrell D Belke

Abstract

Hemoglobin A1c (HbA1c) is the predominant diagnostic tool for diabetes diagnosis and progression. However, it has proven to be insensitive at pre-diabetic threshold values. O-linked-β-N-acetylglucosamine (O-GlcNAc) modification has emerged as a sensitive biomarker. The purpose of this study was to explore the sensitivity of O-GlcNAc expression as a potential marker of early metabolic dysfunction in a young adult population. Healthy, young males (18-35 y) from the Assessing Inherited Metabolic syndrome Markers in the Young study (AIMMY), were divided into low (LH,0.60) or high (HH,1.61) homeostatic model assessment of insulin resistance (HOMA-IR) cohorts.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 18%
Student > Master 6 15%
Student > Ph. D. Student 5 13%
Other 4 10%
Student > Bachelor 2 5%
Other 6 15%
Unknown 10 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 28%
Chemistry 4 10%
Medicine and Dentistry 4 10%
Nursing and Health Professions 3 8%
Biochemistry, Genetics and Molecular Biology 3 8%
Other 4 10%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 October 2014.
All research outputs
#17,730,142
of 22,768,097 outputs
Outputs from Diabetology & Metabolic Syndrome
#430
of 662 outputs
Outputs of similar age
#160,639
of 238,621 outputs
Outputs of similar age from Diabetology & Metabolic Syndrome
#7
of 22 outputs
Altmetric has tracked 22,768,097 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 662 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,621 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.