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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies
|
|---|---|
| Published in |
Acta Neuropathologica Communications, July 2014
|
| DOI | 10.1186/2051-5960-2-71 |
| Pubmed ID | |
| Authors |
Joan Liu, Cheryl Reeves, Zuzanna Michalak, Antonietta Coppola, Beate Diehl, Sanjay M Sisodiya, Maria Thom |
| Abstract |
Activation of the mTOR pathway has been linked to the cytopathology and epileptogenicity of malformations, specifically Focal Cortical Dysplasia (FCD) and Tuberous Sclerosis (TSC). Experimental and clinical trials have shown than mTOR inhibitors have anti-epileptogenic effects in TS. Dysmorphic neurones and balloon cells are hallmarks of FCDIIb and TSC, but similar cells are also occasionally observed in other acquired epileptogenic pathologies, including hippocampal sclerosis (HS) and Rasmussen's encephalitis (RE). Our aim was to explore mTOR pathway activation in a range of epilepsy-associated pathologies and in lesion-negative cases. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| United States | 1 | 1% |
| Ethiopia | 1 | 1% |
| Unknown | 94 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 14% |
| Researcher | 14 | 14% |
| Student > Master | 10 | 10% |
| Student > Bachelor | 10 | 10% |
| Other | 6 | 6% |
| Other | 20 | 21% |
| Unknown | 23 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 31% |
| Neuroscience | 12 | 12% |
| Biochemistry, Genetics and Molecular Biology | 11 | 11% |
| Agricultural and Biological Sciences | 9 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Other | 5 | 5% |
| Unknown | 27 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2014.
All research outputs
#17,291,019
of 25,393,455 outputs
Outputs from Acta Neuropathologica Communications
#1,312
of 1,576 outputs
Outputs of similar age
#143,600
of 240,026 outputs
Outputs of similar age from Acta Neuropathologica Communications
#12
of 18 outputs
Altmetric has tracked 25,393,455 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,576 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,026 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.