Title |
Histologic and spectroscopic study of pluripotent stem cells after implant in ocular traumatic injuries in a murine model
|
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Published in |
Stem Cell Research & Therapy, October 2014
|
DOI | 10.1186/scrt509 |
Pubmed ID | |
Authors |
Gustavo Jesús Vázquez-Zapién, Marlon Rojas-López, Raúl Jacobo Delgado-Macuil, Luis Rubén Martínez-Nava, David Guillermo Pérez-Ishiwara, Mónica Maribel Mata-Miranda |
Abstract |
The ocular trauma is defined as a trauma caused by blunt or penetrating mechanisms on the eyeball and its peripheral structures, causing damage with different degrees of affectation with temporary or permanent visual function compromise. The ocular trauma is a major cause of preventable blindness worldwide; it constitutes the 7% of all corporal injury, and 10-15% of all eye diseases. The regenerative medicine research has opened the possibility to use stem cells as a source of cell replacement; so that experimental studies on embryonic stem cells and bone marrow stem cells have been carried out. In this study we analyzed the histopathological and spectroscopic changes in ocular tissue with trauma, treated with mouse pluripotent stem cells. |
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