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Design of the SALT Osteoporosis Study: a randomised pragmatic trial, to study a primary care screening and treatment program for the prevention of fractures in women aged 65 years or older

Overview of attention for article published in BMC Musculoskeletal Disorders, October 2017
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Title
Design of the SALT Osteoporosis Study: a randomised pragmatic trial, to study a primary care screening and treatment program for the prevention of fractures in women aged 65 years or older
Published in
BMC Musculoskeletal Disorders, October 2017
DOI 10.1186/s12891-017-1783-y
Pubmed ID
Authors

P. J. M. Elders, T. Merlijn, K. M. A. Swart, W. van Hout, B. C. van der Zwaard, C. Niemeijer, M. W. Heymans, A. A. van der Heijden, F. Rutters, H. E. van der Horst, P. Lips, J. C. Netelenbos, N. M. van Schoor

Abstract

Several drugs have become available for the treatment of osteoporosis. However, screening and treatment of patients with a high fracture risk is currently not recommended in the Netherlands, because the effectiveness of bone sparing drugs has not been demonstrated in the general primary care population. Here we describe the design of the SALT Osteoporosis study, which aims to examine whether the screening and treatment of older, female patients in primary care can reduce fractures, in comparison to usual care. A randomised pragmatic trial has been designed using a stepwise approach in general care practices in the Netherlands. Women aged ≥65 years, who are not prescribed bone sparing drugs or corticosteroids are eligible for the study. First, women with at least one clinical risk factor for fractures, as determined by questionnaires, are randomly assigned to the intervention or control group. Second, women in the intervention group having a high fracture risk according to our screening program, including an adapted fracture risk assessment (FRAX) tool, combined with dual-energy x-ray absorptiometry (DXA), and instant vertebral assessment (IVA), are offered a structured treatment program. The women in the control group receive care as usual and will undergo the same screening as the intervention group at the end of the trial. The follow-up duration will be three years and the primary outcome is time to first incident fracture and the total number of fractures. The results of the current study will be very important for underpinnings of the prevention strategy of the osteoporosis guidelines. ID NTR2430 . Registered 26 July 2010.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 57 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 19%
Student > Bachelor 10 18%
Student > Master 4 7%
Lecturer 3 5%
Professor > Associate Professor 3 5%
Other 9 16%
Unknown 17 30%
Readers by discipline Count As %
Medicine and Dentistry 19 33%
Nursing and Health Professions 9 16%
Unspecified 2 4%
Biochemistry, Genetics and Molecular Biology 2 4%
Social Sciences 2 4%
Other 5 9%
Unknown 18 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2017.
All research outputs
#14,830,010
of 23,007,053 outputs
Outputs from BMC Musculoskeletal Disorders
#2,298
of 4,091 outputs
Outputs of similar age
#192,057
of 328,368 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#46
of 76 outputs
Altmetric has tracked 23,007,053 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,091 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,368 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.