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Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor–positive breast cancers

Overview of attention for article published in Breast Cancer Research, October 2014
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Citations

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33 Mendeley
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Title
Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor–positive breast cancers
Published in
Breast Cancer Research, October 2014
DOI 10.1186/s13058-014-0447-1
Pubmed ID
Authors

Ricardo Ribas, Zara Ghazoui, Qiong Gao, Sunil Pancholi, Aradhana Rani, Anita Dunbier, Mitch Dowsett, Lesley-Ann Martin

Abstract

Endocrine therapies target oestrogenic stimulation of breast cancer (BC) growth, but resistance remains problematic. Our aims in this study were (1) to identify genes most strongly associated with resistance to endocrine therapy by intersecting global gene transcription data from patients treated presurgically with the aromatase inhibitor anastrazole with those from MCF7 cells adapted to long-term oestrogen deprivation (LTED) (2) to assess the clinical value of selected genes in public clinical data sets and (3) to determine the impact of targeting these genes with novel agents.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 18%
Researcher 6 18%
Student > Master 3 9%
Student > Bachelor 2 6%
Student > Doctoral Student 1 3%
Other 4 12%
Unknown 11 33%
Readers by discipline Count As %
Medicine and Dentistry 8 24%
Biochemistry, Genetics and Molecular Biology 5 15%
Agricultural and Biological Sciences 4 12%
Nursing and Health Professions 1 3%
Chemistry 1 3%
Other 0 0%
Unknown 14 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2015.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from Breast Cancer Research
#1,706
of 2,053 outputs
Outputs of similar age
#201,011
of 274,545 outputs
Outputs of similar age from Breast Cancer Research
#43
of 55 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,053 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,545 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.