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Antifungal susceptibility and phenotypic virulence markers of Candida species isolated from Nepal

Overview of attention for article published in BMC Research Notes, November 2017
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Title
Antifungal susceptibility and phenotypic virulence markers of Candida species isolated from Nepal
Published in
BMC Research Notes, November 2017
DOI 10.1186/s13104-017-2852-x
Pubmed ID
Authors

Supram Hosuru Subramanya, Bharat Prasad Baral, Nawal Kishor Sharan, Niranjan Nayak, Yang Metok, Brijesh Sathian, Indira Bairy, Shishir Gokhale

Abstract

Candida species are part of the commensal microflora in many anatomical sites of the human body; however, breach in the integrity of the body part and impaired immunity of the host can lead to invasive candidiasis. A number of virulence determinants could contribute towards its pathogenicity. Thus we attempted to evaluate the in vitro expression of different virulence factors among clinical isolates of Candida species and assayed their susceptibility patterns against a range of antifungal agents. Of the total of 71 isolates we obtained, 48 (67.6%) were Candida albicans, 11 (15.49%) Candida tropicalis, 09 (12.67%) Candida glabrata and 03 (4.22%) were Candida krusei. Proteinase, phospholipase and esterase production could be revealed amongst 43 (60.56%), 44 (61.97%) and 49 (69.01%) isolates respectively. None of the isolates showed DNAase activity. Fifty-five (77.39%) isolates were biofilm producers, and 53 (74.6%) exhibited high cell surface hydrophobicity.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 17%
Student > Master 6 13%
Lecturer 4 9%
Student > Bachelor 3 7%
Student > Ph. D. Student 3 7%
Other 7 15%
Unknown 15 33%
Readers by discipline Count As %
Immunology and Microbiology 10 22%
Medicine and Dentistry 6 13%
Agricultural and Biological Sciences 4 9%
Veterinary Science and Veterinary Medicine 2 4%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 2 4%
Unknown 20 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2018.
All research outputs
#16,357,504
of 24,093,053 outputs
Outputs from BMC Research Notes
#2,402
of 4,361 outputs
Outputs of similar age
#211,137
of 333,301 outputs
Outputs of similar age from BMC Research Notes
#75
of 148 outputs
Altmetric has tracked 24,093,053 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,361 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,301 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 148 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.