Title |
Epidemiology and genetic diversity of bovine leukemia virus
|
---|---|
Published in |
Virology Journal, November 2017
|
DOI | 10.1186/s12985-017-0876-4 |
Pubmed ID | |
Authors |
Meripet Polat, Shin-nosuke Takeshima, Yoko Aida |
Abstract |
Bovine leukemia virus (BLV), an oncogenic member of the Deltaretrovirus genus, is closely related to human T-cell leukemia virus (HTLV-I and II). BLV infects cattle worldwide and causes important economic losses. In this review, we provide a summary of available information about commonly used diagnostic approaches for the detection of BLV infection, including both serological and viral genome-based methods. We also outline genotyping methods used for the phylogenetic analysis of BLV, including PCR restriction length polymorphism and modern DNA sequencing-based methods. In addition, detailed epidemiological information on the prevalence of BLV in cattle worldwide is presented. Finally, we summarize the various BLV genotypes identified by the phylogenetic analyses of the whole genome and env gp51 sequences of BLV strains in different countries and discuss the distribution of BLV genotypes worldwide. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 14% |
Unknown | 12 | 86% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 93% |
Practitioners (doctors, other healthcare professionals) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 202 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 31 | 15% |
Student > Master | 26 | 13% |
Researcher | 24 | 12% |
Student > Ph. D. Student | 18 | 9% |
Student > Doctoral Student | 14 | 7% |
Other | 33 | 16% |
Unknown | 56 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 60 | 30% |
Agricultural and Biological Sciences | 34 | 17% |
Biochemistry, Genetics and Molecular Biology | 20 | 10% |
Immunology and Microbiology | 11 | 5% |
Medicine and Dentistry | 8 | 4% |
Other | 6 | 3% |
Unknown | 63 | 31% |