Title |
Chronic urticaria: new management options
|
---|---|
Published in |
World Allergy Organization Journal, November 2014
|
DOI | 10.1186/1939-4551-7-31 |
Pubmed ID | |
Authors |
Paul A Greenberger |
Abstract |
Chronic urticaria is defined as episodic or daily hives lasting for at least 6 weeks and impairs quality of life. Two main subtypes include chronic idiopathic (spontaneous) urticaria and inducible (physical) urticaria, but some patients have urticarial vasculitis. "Autoimmune chronic urticaria" implies the presence of histamine releasing or mast cell activating autoantibodies to IgE or FcϵRI, the high affinity receptor on mast cells and basophils. In patients not readily controlled with labeled dosages of second generation H1 receptor antagonists (antihistamines), there is evidence for reduction of urticaria using up to 4 fold increases in labeled dosages. The biologic modifier, omalizumab, helps to reduce lesions of chronic urticaria within 1-2 weeks. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 33% |
United Kingdom | 2 | 17% |
Argentina | 1 | 8% |
Germany | 1 | 8% |
Unknown | 4 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 50% |
Practitioners (doctors, other healthcare professionals) | 3 | 25% |
Scientists | 3 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 1% |
United States | 1 | 1% |
Bulgaria | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 78 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 13% |
Other | 10 | 12% |
Student > Postgraduate | 10 | 12% |
Researcher | 7 | 9% |
Student > Doctoral Student | 6 | 7% |
Other | 17 | 21% |
Unknown | 21 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 39 | 48% |
Agricultural and Biological Sciences | 5 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 2% |
Immunology and Microbiology | 2 | 2% |
Other | 9 | 11% |
Unknown | 22 | 27% |