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Vitamin C treatment attenuates hemorrhagic shock related multi-organ injuries through the induction of heme oxygenase-1

Overview of attention for article published in BMC Complementary Medicine and Therapies, November 2014
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3 X users

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23 Mendeley
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Title
Vitamin C treatment attenuates hemorrhagic shock related multi-organ injuries through the induction of heme oxygenase-1
Published in
BMC Complementary Medicine and Therapies, November 2014
DOI 10.1186/1472-6882-14-442
Pubmed ID
Authors

Bing Zhao, Jian Fei, Ying Chen, Yi-Lin Ying, Li Ma, Xiao-Qin Song, Jie Huang, Er-Zhen Chen, En-Qiang Mao

Abstract

Vitamin C (VitC) has recently been shown to exert beneficial effects, including protecting organ function and inhibiting inflammation, in various critical care conditions, but the specific mechanism remains unclear. Induction of heme oxygenase (HO)-1, a heat shock protein, has been shown to prevent organ injuries in hemorrhagic shock (HS) but the relationship between VitC and HO-1 are still ill-defined so far. Here we conducted a systemic in vivo study to investigate if VitC promoted HO-1 expression in multiple organs, and then tested if the HO-1 induction property of VitC was related to its organ protection and anti-inflammatory effect.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 17%
Student > Master 4 17%
Student > Doctoral Student 3 13%
Professor > Associate Professor 2 9%
Other 1 4%
Other 4 17%
Unknown 5 22%
Readers by discipline Count As %
Medicine and Dentistry 13 57%
Unspecified 1 4%
Agricultural and Biological Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Unknown 7 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2014.
All research outputs
#14,789,596
of 22,770,070 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,832
of 3,623 outputs
Outputs of similar age
#143,104
of 258,738 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#65
of 121 outputs
Altmetric has tracked 22,770,070 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,623 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 258,738 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 121 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.