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Keratitis by Fusarium temperatum, a novel opportunist

Overview of attention for article published in BMC Infectious Diseases, November 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

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4 tweeters

Citations

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36 Dimensions

Readers on

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49 Mendeley
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Title
Keratitis by Fusarium temperatum, a novel opportunist
Published in
BMC Infectious Diseases, November 2014
DOI 10.1186/s12879-014-0588-y
Pubmed ID
Authors

Abdullah M S Al-Hatmi, Alexandro Bonifaz, G Sybren de Hoog, Leticia Vazquez-Maya, Karla Garcia-Carmona, Jacques F Meis, Anne D van Diepeningen

Abstract

Background Fusarium species are among the most common fungi present in the environment and some species have emerged as major opportunistic fungal infection in human. However, in immunocompromised hosts they can be virulent pathogens and can cause death. The pathogenesis of this infection relies on three factors: colonization, tissue damage, and immunosuppression. A novel Fusarium species is reported for the first time from keratitis in an agriculture worker who acquired the infection from plant material of maize. Maize plants are the natural host of this fungus where it causes stalk rot and seeding malformation under temperate and humid climatic conditions. The clinical manifestation, microbiological morphology, physiological features and molecular data are described.MethodsDiagnosis was established by using polymerase chain reaction of fungal DNA followed by sequencing portions of translation elongation factor 1 alpha (TEF1 ¿) and beta-tubulin (BT2) genes. Susceptibility profiles of this fungus were evaluated using CLSI broth microdilution method.ResultsThe analyses of these two genes sequences support a novel opportunist with the designation Fusarium temperatum. Phylogenetic analyses showed that the reported clinical isolate was nested within the Fusarium fujikuroi species complex. Antifungal susceptibility testing demonstrated that the fungus had low MICs of micafungin (0.031 ¿g/ml), posaconazole (0.25 ¿g/ml) and amphotericin B (0.5 ¿g/ml).ConclusionThe present case extends the significance of the genus Fusarium as agents of keratitis and underscores the utility of molecular verification of these emerging fungi in the human host.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 20%
Student > Bachelor 8 16%
Student > Postgraduate 7 14%
Researcher 7 14%
Other 5 10%
Other 4 8%
Unknown 8 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 47%
Medicine and Dentistry 7 14%
Immunology and Microbiology 4 8%
Biochemistry, Genetics and Molecular Biology 2 4%
Engineering 2 4%
Other 2 4%
Unknown 9 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 November 2014.
All research outputs
#13,183,066
of 22,770,070 outputs
Outputs from BMC Infectious Diseases
#3,159
of 7,668 outputs
Outputs of similar age
#120,765
of 258,738 outputs
Outputs of similar age from BMC Infectious Diseases
#63
of 190 outputs
Altmetric has tracked 22,770,070 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,668 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 258,738 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 190 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.