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Long-term cost effectiveness of ticagrelor in patients with acute coronary syndromes in Thailand

Overview of attention for article published in Health Economics Review, November 2014
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Title
Long-term cost effectiveness of ticagrelor in patients with acute coronary syndromes in Thailand
Published in
Health Economics Review, November 2014
DOI 10.1186/s13561-014-0017-3
Pubmed ID
Authors

Sukit Yamwong, Unchalee Permsuwan, Sirana Tinmanee, Piyamitr Sritara

Abstract

To evaluate the long-term cost-effectiveness of ticagrelor and ASA versus generic and branded clopidogrel and ASA in patients with ACS based on a Thai cost database. A one-year decision tree and a long-term Markov model were constructed to estimate lifetime costs and quality-adjusted life years (QALYs). For the first year, data from PLATO (NCT00391872) were used to estimate the rate of cardiovascular events, resource use, and QALYs. For year 2 onwards, clinical effectiveness was estimated conditional on individual health states that occurred during the first year. In the base-case analysis, the incremental cost-effectiveness ratio (ICER) with ticagrelor was 292,504 ($9,476) and 60,055 ($1,946) THB($)/QALY compared with generic and branded clopidogrel, respectively. The probability of ticagrelor being cost-effective was above 99% at a threshold of 160,000 THB/QALY compared with branded clopidogrel. This health economic analysis provides cost effectiveness data for ticagrelor compared with both generic and branded clopidogrel in Thailand. Based on this analysis, it appears that ticagrelor is an economically valuable treatment for ACS compared with branded clopidogrel within the Thai context.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 19%
Researcher 4 15%
Student > Bachelor 3 11%
Student > Ph. D. Student 2 7%
Lecturer 2 7%
Other 4 15%
Unknown 7 26%
Readers by discipline Count As %
Medicine and Dentistry 8 30%
Economics, Econometrics and Finance 3 11%
Computer Science 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Nursing and Health Professions 2 7%
Other 1 4%
Unknown 9 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2014.
All research outputs
#20,242,779
of 22,770,070 outputs
Outputs from Health Economics Review
#407
of 427 outputs
Outputs of similar age
#215,365
of 258,049 outputs
Outputs of similar age from Health Economics Review
#17
of 18 outputs
Altmetric has tracked 22,770,070 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.