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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis
|
|---|---|
| Published in |
Critical Care, November 2014
|
| DOI | 10.1186/s13054-014-0602-1 |
| Pubmed ID | |
| Authors |
Anne Julie Frenette, Josée Bouchard, Pascaline Bernier, Annie Charbonneau, Long Thanh Nguyen, Jean-Philippe Rioux, Stéphan Troyanov, David R Williamson |
| Abstract |
IntroductionThe risk of acute kidney injury (AKI) with the use of albumin-containing fluids compared to starches in the surgical intensive care setting remains uncertain. We evaluated the adjusted risk of AKI associated with colloids following cardiac surgery.MethodsWe performed a retrospective cohort study of patients undergoing on-pump cardiac surgery in a tertiary care center from 2008 to 2010. We assessed crystalloid and colloid administration until 36 hours postoperatively. AKI was defined by the Risk Injury Failure Loss and End-stage kidney disease (RIFLE risk) and Acute Kidney Injury Network (AKIN) stage 1 serum creatinine criterion within 96 hours postoperatively.ResultsOur cohort included 984 patients with a baseline glomerular filtration rate of 72¿±¿19 ml/min/1.73 m2. Twenty-three percent had a reduced left ventricular ejection fraction (LVEF), 31% were diabetics and 23% underwent valvular surgery. The incidence of AKI was 5.3% with RIFLE and 12.0% with AKIN. AKI was associated with a reduced LVEF, diuretic use, anemia, valvular surgery, duration of extracorporeal circulation, hemodynamic instability, and the use of albumin, pentastarch 10% and transfusions. There was an important dose-dependent AKI risk with the administration of albumin, which also paralleled a higher prevalence of concomitant risk factors of AKI. To address any indication bias, we derived a propensity score predicting the likelihood to receive albumin, matching 141 cases to 141 controls with a similar risk profile. In this analysis, albumin was associated with an increased AKI risk (RIFLE Risk 12% versus 5%, P =0.03 and AKIN stage 1 28% versus 13%, P =0.002). We repeated this methodology in subjects without postoperative hemodynamic instability and still identified an association between the use of albumin and AKI.ConclusionsAlbumin administration was associated with a dose-dependent risk of AKI and remained significant using a propensity score methodology. Future studies should address the safety of albumin-containing fluids on kidney function in patients undergoing cardiac surgery. |
X Demographics
The data shown below were collected from the profiles of 37 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | 14% |
| Spain | 3 | 8% |
| El Salvador | 2 | 5% |
| South Africa | 1 | 3% |
| Turkey | 1 | 3% |
| Greece | 1 | 3% |
| United States | 1 | 3% |
| Netherlands | 1 | 3% |
| Australia | 1 | 3% |
| Other | 3 | 8% |
| Unknown | 18 | 49% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 26 | 70% |
| Practitioners (doctors, other healthcare professionals) | 7 | 19% |
| Science communicators (journalists, bloggers, editors) | 3 | 8% |
| Scientists | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 1% |
| United States | 1 | 1% |
| Italy | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 89 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 19% |
| Other | 13 | 14% |
| Student > Ph. D. Student | 8 | 9% |
| Professor > Associate Professor | 8 | 9% |
| Student > Bachelor | 8 | 9% |
| Other | 26 | 28% |
| Unknown | 12 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 59 | 63% |
| Agricultural and Biological Sciences | 6 | 6% |
| Nursing and Health Professions | 3 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Decision Sciences | 2 | 2% |
| Other | 4 | 4% |
| Unknown | 16 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2016.
All research outputs
#1,680,101
of 25,373,627 outputs
Outputs from Critical Care
#1,475
of 6,554 outputs
Outputs of similar age
#18,909
of 269,845 outputs
Outputs of similar age from Critical Care
#14
of 171 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,845 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 171 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.