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Initial and long-term evaluation of patients with Alzheimer’s after hospitalization in cognitive and behavioural units: the EVITAL study design

Overview of attention for article published in BMC Psychiatry, November 2014
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Title
Initial and long-term evaluation of patients with Alzheimer’s after hospitalization in cognitive and behavioural units: the EVITAL study design
Published in
BMC Psychiatry, November 2014
DOI 10.1186/s12888-014-0308-6
Pubmed ID
Authors

Elodie Pongan, Magalie Freulon, Floriane Delphin-Combe, Florence Dibie-Racoupeau, Géraldine Martin-Gaujard, Denis Federico, Aziza Waissi, Gaëlle Richard, Sophie Jacqueline, Florence Fabre, Béatrice Trombert-Paviot, Pierre Krolak-Salmon, Bernard Laurent, Isabelle Rouch

Abstract

BackgroundAlzheimer¿s disease and related disorders are characterized by cognitive impairment associated with behavioral and psychological symptoms of dementia. These symptoms have significant consequences for both the patient and his family environment. While risk factors for behavioral disorders have been identified in several studies, few studies have focused on the evolution of these disorders. Moreover, it is important to identify factors linked to the long-term evolution of behavioral disorders, as well as patients¿ and caregivers¿ quality of life. Our purpose is to present the methodology of the EVITAL study, which primary objective is to determine the factors associated with the evolution of behavioral disorders among patients with Alzheimer¿s disease and related disorders during the year following their hospitalization in cognitive and behavioral units. Secondary objectives were 1) to assess the factors related to the evolution of behavioral disorders during hospitalization in cognitive and behavioral units; 2) to identify the factors linked to patients¿ and caregivers¿ quality of life, as well as caregivers¿ burden; 3) to assess the factors associated with rehospitalization of the patients for behavioral disorders in the year following their hospitalization in cognitive and behavioral units.Method/designA multicenter, prospective cohort of patients with Alzheimer¿s disease and related disorders as well as behavioral disorders who are hospitalized in cognitive and behavioral units.The patients will be included in the study for a period of 24 months and followed-up for 12 months. Socio-demographic and environmental data, behavioral disorders, medications, patients¿ and caregivers¿ quality of life as well as caregivers¿ burden will be assessed throughout hospitalization in cognitive and behavioral units. Follow-up will be performed at months 3, 6 and 12 after hospitalization. Socio-demographic and environmental data, behavioral disorders, medications, patients¿ and caregivers¿ quality of life, unplanned rehospitalization as well as caregivers¿ burden will also be assessed at each follow-up interview.DiscussionThe present study should help better identify the factors associated with reduction or stabilization of the behavioral and psychological symptoms of dementia in patients with Alzheimer¿s disease. It could therefore help clinicians to better manage these symptoms.Trial registrationClinical Trials NCT01901263. Registered July 9, 2013.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 76 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 13 17%
Student > Master 11 14%
Student > Ph. D. Student 7 9%
Researcher 5 6%
Student > Doctoral Student 5 6%
Other 15 19%
Unknown 21 27%
Readers by discipline Count As %
Medicine and Dentistry 19 25%
Nursing and Health Professions 14 18%
Psychology 8 10%
Engineering 3 4%
Agricultural and Biological Sciences 2 3%
Other 8 10%
Unknown 23 30%