Title |
Hepatoprotective and antioxidant activities of extracts from Salvia—Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet in mice
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Published in |
Journal of Translational Medicine, November 2014
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DOI | 10.1186/s12967-014-0315-x |
Pubmed ID | |
Authors |
Yang Liu, Haiyan Song, Lei Wang, Hanchen Xu, Xiangbing Shu, Li Zhang, Ying Li, Dongfei Li, Guang Ji |
Abstract |
Nonalcoholic steatohepatitis (NASH), the advanced stage of nonalcoholic fatty liver disease that is characterized by both steatosis and severe injury in liver, still lacks efficient treatment. The traditional Chinese formula Salvia-Nelumbinis naturalis (SNN) is effectively applied to improve the symptoms of nonalcoholic simple fatty liver (NAFL) patients. Previous studies have confirmed that SNN could reduce the liver lipid deposition and serum transaminases of NAFL experimental models. This study aims to determine whether SNN is effective for murine NASH model and investigate the underlying pharmacological mechanisms. |
X Demographics
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 33 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 6 | 18% |
Student > Master | 6 | 18% |
Student > Bachelor | 3 | 9% |
Researcher | 3 | 9% |
Unspecified | 2 | 6% |
Other | 4 | 12% |
Unknown | 9 | 27% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 6 | 18% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 15% |
Medicine and Dentistry | 3 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 9% |
Unspecified | 2 | 6% |
Other | 4 | 12% |
Unknown | 10 | 30% |