You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Chromatin accessibility: a window into the genome
|
|---|---|
| Published in |
Epigenetics & Chromatin, November 2014
|
| DOI | 10.1186/1756-8935-7-33 |
| Pubmed ID | |
| Authors |
Maria Tsompana, Michael J Buck |
| Abstract |
Transcriptional activation throughout the eukaryotic lineage has been tightly linked with disruption of nucleosome organization at promoters, enhancers, silencers, insulators and locus control regions due to transcription factor binding. Regulatory DNA thus coincides with open or accessible genomic sites of remodeled chromatin. Current chromatin accessibility assays are used to separate the genome by enzymatic or chemical means and isolate either the accessible or protected locations. The isolated DNA is then quantified using a next-generation sequencing platform. Wide application of these assays has recently focused on the identification of the instrumental epigenetic changes responsible for differential gene expression, cell proliferation, functional diversification and disease development. Here we discuss the limitations and advantages of current genome-wide chromatin accessibility assays with especial attention on experimental precautions and sequence data analysis. We conclude with our perspective on future improvements necessary for moving the field of chromatin profiling forward. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 31% |
| United States | 1 | 8% |
| France | 1 | 8% |
| Germany | 1 | 8% |
| Canada | 1 | 8% |
| Unknown | 5 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 54% |
| Scientists | 4 | 31% |
| Science communicators (journalists, bloggers, editors) | 2 | 15% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,189 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 16 | 1% |
| France | 3 | <1% |
| United Kingdom | 3 | <1% |
| Germany | 2 | <1% |
| Korea, Republic of | 2 | <1% |
| Denmark | 2 | <1% |
| Japan | 2 | <1% |
| Israel | 1 | <1% |
| Canada | 1 | <1% |
| Other | 4 | <1% |
| Unknown | 1153 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 317 | 27% |
| Researcher | 205 | 17% |
| Student > Master | 162 | 14% |
| Student > Bachelor | 119 | 10% |
| Student > Doctoral Student | 66 | 6% |
| Other | 115 | 10% |
| Unknown | 205 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 382 | 32% |
| Agricultural and Biological Sciences | 373 | 31% |
| Medicine and Dentistry | 39 | 3% |
| Computer Science | 33 | 3% |
| Neuroscience | 30 | 3% |
| Other | 99 | 8% |
| Unknown | 233 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2024.
All research outputs
#1,664,956
of 25,089,705 outputs
Outputs from Epigenetics & Chromatin
#33
of 611 outputs
Outputs of similar age
#22,411
of 374,749 outputs
Outputs of similar age from Epigenetics & Chromatin
#1
of 14 outputs
Altmetric has tracked 25,089,705 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 611 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 374,749 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.