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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Tumorigenesis as a process of gradual loss of original cell identity and gain of properties of neural precursor/progenitor cells
|
|---|---|
| Published in |
Cell & Bioscience, November 2017
|
| DOI | 10.1186/s13578-017-0188-9 |
| Pubmed ID | |
| Authors |
Ying Cao |
| Abstract |
Cancer is a complex disease without a unified explanation for its cause so far. Our recent work demonstrates that cancer cells share similar regulatory networks and characteristics with embryonic neural cells. Based on the study, I will address the relationship between tumor and neural cells in more details. I collected the evidence from various aspects of cancer development in many other studies, and integrated the information from studies on cancer cell properties, cell fate specification during embryonic development and evolution. Synthesis of the information strongly supports that cancer cells share much more similarities with neural progenitor/stem cells than with mesenchymal-type cells and that tumorigenesis represents a process of gradual loss of cell or lineage identity and gain of characteristics of neural cells. I also discuss cancer EMT, a concept having been under intense debate, and possibly the true meaning of EMT in cancer initiation and development. This synthesis provides fresh insights into a unified explanation for and a previously unrecognized nature of tumorigenesis, which might not be revealed by studies on individual molecular events. The review will also present some brief suggestions for cancer research based on the proposed model of tumorigenesis. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 70% |
| Scientists | 1 | 10% |
| Unknown | 2 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 168 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 168 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 28 | 17% |
| Student > Master | 21 | 13% |
| Student > Ph. D. Student | 20 | 12% |
| Researcher | 16 | 10% |
| Other | 5 | 3% |
| Other | 14 | 8% |
| Unknown | 64 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 47 | 28% |
| Agricultural and Biological Sciences | 14 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
| Medicine and Dentistry | 6 | 4% |
| Chemistry | 6 | 4% |
| Other | 20 | 12% |
| Unknown | 69 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 216. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2024.
All research outputs
#166,125
of 24,203,404 outputs
Outputs from Cell & Bioscience
#2
of 1,065 outputs
Outputs of similar age
#3,622
of 335,669 outputs
Outputs of similar age from Cell & Bioscience
#2
of 14 outputs
Altmetric has tracked 24,203,404 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,065 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,669 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.