Title |
Effects of helminth co-infections on atopy, asthma and cytokine production in children living in a poor urban area in Latin America
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Published in |
BMC Research Notes, November 2014
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DOI | 10.1186/1756-0500-7-817 |
Pubmed ID | |
Authors |
Neuza Maria Alcântara-Neves, Gabriela de S G Britto, Rafael Valente Veiga, Camila A Figueiredo, Rosimeire Leovigildo Fiaccone, Jackson S da Conceição, Álvaro Augusto Cruz, Laura Cunha Rodrigues, Philip John Cooper, Lain C Pontes-de-Carvalho, Maurício Lima Barreto |
Abstract |
Helminths are modulators of the host immune system, and infections with these parasites have been associated with protection against allergies and autoimmune diseases. The human host is often infected with multiple helminth parasites and most studies to date have investigated the effects of helminths in the context of infections with single parasite or types of parasites (e.g. geohelminths). In this study, we investigated how co-infections with three nematodes affect markers of allergic inflammation and asthma in children. We selected Ascaris lumbricoides and Trichuris trichiura, two parasites that inhabit the human intestine and Toxocara spp (Toxocara canis and/or T. cati), intestinal roundworms of dogs and cats that cause systemic larval infection in humans. These parasites were selected as the most prevalent helminth parasites in our study population. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 22% |
Mexico | 1 | 11% |
Canada | 1 | 11% |
France | 1 | 11% |
Unknown | 4 | 44% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 78% |
Practitioners (doctors, other healthcare professionals) | 1 | 11% |
Scientists | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | <1% |
Unknown | 121 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 20 | 16% |
Student > Master | 17 | 14% |
Student > Ph. D. Student | 14 | 11% |
Professor | 11 | 9% |
Researcher | 9 | 7% |
Other | 22 | 18% |
Unknown | 29 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 37 | 30% |
Agricultural and Biological Sciences | 15 | 12% |
Immunology and Microbiology | 12 | 10% |
Biochemistry, Genetics and Molecular Biology | 8 | 7% |
Social Sciences | 3 | 2% |
Other | 14 | 11% |
Unknown | 33 | 27% |