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Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses

Overview of attention for article published in BMC Cancer, November 2014
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Mentioned by

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2 tweeters
facebook
1 Facebook page

Citations

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14 Dimensions

Readers on

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28 Mendeley

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Title
Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses
Published in
BMC Cancer, November 2014
DOI 10.1186/1471-2407-14-857
Pubmed ID
25413220
Authors

Lin Jiang, Cécile Campagne, Elisabeth Sundström, Pedro Sousa, Saima Imran, Monika Seltenhammer, Gerli Pielberg, Mats J Olsson, Giorgia Egidy, Leif Andersson, Anna Golovko

Abstract

Constitutive activation of the ERK pathway, occurring in the vast majority of melanocytic neoplasms, has a pivotal role in melanoma development. Different mechanisms underlie this activation in different tumour settings. The Grey phenotype in horses, caused by a 4.6 kb duplication in intron 6 of Syntaxin 17 (STX17), is associated with a very high incidence of cutaneous melanoma, but the molecular mechanism behind the melanomagenesis remains unknown. Here, we investigated the involvement of the ERK pathway in melanoma development in Grey horses.

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Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 36%
Student > Ph. D. Student 4 14%
Student > Master 3 11%
Student > Postgraduate 2 7%
Student > Bachelor 2 7%
Other 3 11%
Unknown 4 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 32%
Veterinary Science and Veterinary Medicine 5 18%
Biochemistry, Genetics and Molecular Biology 5 18%
Medicine and Dentistry 3 11%
Immunology and Microbiology 1 4%
Other 1 4%
Unknown 4 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2018.
All research outputs
#7,756,675
of 12,362,966 outputs
Outputs from BMC Cancer
#2,216
of 4,556 outputs
Outputs of similar age
#138,065
of 271,052 outputs
Outputs of similar age from BMC Cancer
#208
of 460 outputs
Altmetric has tracked 12,362,966 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,556 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,052 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 460 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.

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