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Resveratrol plus carboxymethyl-β-glucan in children with recurrent respiratory infections: a preliminary and real-life experience

Overview of attention for article published in Italian Journal of Pediatrics, November 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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2 tweeters
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1 patent

Citations

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22 Dimensions

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46 Mendeley
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Title
Resveratrol plus carboxymethyl-β-glucan in children with recurrent respiratory infections: a preliminary and real-life experience
Published in
Italian Journal of Pediatrics, November 2014
DOI 10.1186/s13052-014-0093-3
Pubmed ID
Authors

Alfonso Maria Varricchio, Michele Capasso, Antonio della Volpe, Luigi Malafronte, Nicola Mansi, Attilio Varricchio, Giorgio Ciprandi

Abstract

BackgroundRecurrent respiratory infections (RRI), such as the presence of at least one of the following criteria: i) >6 RI per year; ii) >1 RI per month involving upper airways from September to April; iii) >3 RI involving lower airways, constitute a social problem for both their pharmaco-economic impact and the burden for the family. However, several treatment have been proposed with controversial results.ObjectiveAs resveratrol plus carboxymethyl-ß-glucan is presently available as solution for aerosol, the aim of this study was to evaluate the effects of this compound, compared to saline solution, whether it is able to prevent RRI in children.DesignThe study was designed as real-life, randomized. Globally, 82 children (49 males, mean age 8.1¿±¿2.6 years) with acute rhinopharyngitis and RRI were enrolled. Resveratrol plus carboxymethyl-ß-glucan or saline isotonic solution was randomly (ratio 1:1) administered immediately after an anti-infective and anti-inflammatory 10-day treatment (tiamphenicol associated with acetylcisteine plus beclomethasone dipropionate) for the acute rhinopharyngitis. Investigated treatments lasted 20 days. Days with respiratory symptoms, fever, medication use, medical visits, and school absences were evaluated. Children were visited 30, 60, and 90 days after starting treatments.ResultsThe active compound was able to significantly reduce the number of days with nasal obstruction (p¿<¿0.001), rhinorrhea (p¿<¿0.001), sneezing (p¿<¿0.001), cough (p¿=¿0.002), fever (p¿<¿0.001), medication use (p¿<¿0.001), medical visits (p¿<¿0.001), and school absence (p¿<¿0.001).ConclusionsThis preliminary and real-life study could suggest that an aerosolized solution containing resveratrol plus carboxymethyl-ß-glucan might exert preventive effects in children with RRI.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 17%
Researcher 6 13%
Student > Master 6 13%
Other 4 9%
Professor 3 7%
Other 7 15%
Unknown 12 26%
Readers by discipline Count As %
Medicine and Dentistry 12 26%
Pharmacology, Toxicology and Pharmaceutical Science 5 11%
Agricultural and Biological Sciences 4 9%
Nursing and Health Professions 2 4%
Social Sciences 2 4%
Other 4 9%
Unknown 17 37%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2018.
All research outputs
#4,190,784
of 14,843,716 outputs
Outputs from Italian Journal of Pediatrics
#110
of 556 outputs
Outputs of similar age
#76,992
of 302,014 outputs
Outputs of similar age from Italian Journal of Pediatrics
#10
of 61 outputs
Altmetric has tracked 14,843,716 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 556 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 302,014 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.