Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage

it seems that the joint lining is very sensitive to hemoglobin and even small amount of blood in the joint fluid after knee trauma can result in significant production of enzymes associated with cartilage damage https://t.co/2sUfmVuee9