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Plasmodium falciparumgene expression measured directly from tissue during human infection

Overview of attention for article published in Genome Medicine, November 2014
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Title
Plasmodium falciparumgene expression measured directly from tissue during human infection
Published in
Genome Medicine, November 2014
DOI 10.1186/s13073-014-0110-6
Pubmed ID
Authors

Daria Van Tyne, Yan Tan, Johanna P Daily, Steve Kamiza, Karl Seydel, Terrie Taylor, Jill P Mesirov, Dyann F Wirth, Danny A Milner

Abstract

During the latter half of the natural 48-h intraerythrocytic life cycle of human Plasmodium falciparum infection, parasites sequester deep in endothelium of tissues, away from the spleen and inaccessible to peripheral blood. These late-stage parasites may cause tissue damage and likely contribute to clinical disease, and a more complete understanding of their biology is needed. Because these life cycle stages are not easily sampled due to deep tissue sequestration, measuring in vivo gene expression of parasites in the trophozoite and schizont stages has been a challenge.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 2%
Canada 1 2%
Unknown 52 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 31%
Student > Ph. D. Student 10 19%
Student > Master 7 13%
Student > Bachelor 4 7%
Other 3 6%
Other 7 13%
Unknown 6 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 35%
Biochemistry, Genetics and Molecular Biology 8 15%
Medicine and Dentistry 5 9%
Immunology and Microbiology 3 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 8 15%
Unknown 9 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2014.
All research outputs
#13,417,604
of 22,772,779 outputs
Outputs from Genome Medicine
#1,227
of 1,437 outputs
Outputs of similar age
#178,431
of 361,775 outputs
Outputs of similar age from Genome Medicine
#60
of 71 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,437 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,775 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.