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Prostatic displacement during extreme hypofractionated radiotherapy using volumetric modulated arc therapy (VMAT)

Overview of attention for article published in Radiation Oncology, November 2014
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Title
Prostatic displacement during extreme hypofractionated radiotherapy using volumetric modulated arc therapy (VMAT)
Published in
Radiation Oncology, November 2014
DOI 10.1186/s13014-014-0262-y
Pubmed ID
Authors

Adam Gladwish, Geordi Pang, Patrick Cheung, Laura D’Alimonte, Andrea Deabreu, Andrew Loblaw

Abstract

BackgroundTo determine prostate displacement during extreme hypofractionated volume modulated arc radiotherapy (VMAT) using pre- and post-treatment orthogonal images with three implanted gold seed fiducial markers.MethodsA total of 150 image pairs were obtained from 30 patients who underwent extreme hypofractionated radiotherapy to a dose of 40 Gy in five fractions on standard linear accelerators. Position verification was obtained with orthogonal x-rays before and after treatment and were used to determine intra-fraction prostate displacement.ResultsThe mean prostate displacements were 0.03¿±¿1.23 mm (1SD), 0.18¿±¿1.55 mm, and 0.37¿±¿1.95 mm in the left-right, superior-inferior, and anterior-posterior directions, respectively. The mean 3D displacement was 2.32¿±¿1.55 mm. Only 6 (4%) fractions had a 3D displacement of >5 mm. The average time of treatment delivery for a given fraction was 195¿±¿59 seconds.ConclusionsThe mean intra-fraction prostate displacement during a course of extreme hypofractionated radiotherapy delivered via VMAT, continues to be small. Clinical margins typically used in a similar fixed-angle IMRT treatment are adequate. The use of VMAT in further extreme hypofractionation may limit prostatic motion uncertainties that would be otherwise be associated with longer treatment times.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 20%
Researcher 6 17%
Student > Bachelor 6 17%
Student > Ph. D. Student 4 11%
Student > Postgraduate 3 9%
Other 8 23%
Unknown 1 3%
Readers by discipline Count As %
Medicine and Dentistry 18 51%
Nursing and Health Professions 5 14%
Philosophy 1 3%
Agricultural and Biological Sciences 1 3%
Computer Science 1 3%
Other 6 17%
Unknown 3 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2014.
All research outputs
#14,791,252
of 22,772,779 outputs
Outputs from Radiation Oncology
#901
of 2,050 outputs
Outputs of similar age
#203,468
of 361,884 outputs
Outputs of similar age from Radiation Oncology
#31
of 85 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,050 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,884 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.