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In vivo screening and evaluation of four herbs against MRSA infections

Overview of attention for article published in BMC Complementary and Alternative Medicine, November 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

twitter
6 tweeters

Citations

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1 Dimensions

Readers on

mendeley
31 Mendeley
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Title
In vivo screening and evaluation of four herbs against MRSA infections
Published in
BMC Complementary and Alternative Medicine, November 2017
DOI 10.1186/s12906-017-2001-z
Pubmed ID
Authors

Najma Arshad, Arifa Mehreen, Iram Liaqat, Muhammad Arshad, Humera Afrasiab

Abstract

Recently, we reported high in vitro antibacterial efficacy of Althaea officinalis, Ziziphus jujuba, Cordia latifolia and Thymus vulgaris out of a total 21 plants against wide range of bacteria including MRSA. This study was therefore, designed to confirm efficacy of these four herbs against MRSA in an animal model. A pilot study was conducted to establish the dose of S. aureus (KY698020) required to induce clinical infection. Afterword, in main trial, efficacy of aforementioned plant extracts on the course of sore throat was checked by evaluating general health, gross lesion score, bacterial load and hematology in mice. Pilot study revealed that 40 μl dose of 10(7) CFU/ml could induce infection which persist upto 08 days post infection. Mice treated with T. vulgaris and Z. jujuba showed reduction in gross lesion score of both heart and lungs. Treatment with only some plants could significantly decrease bacterial load of throat (T. vulgaris) heart, blood and joint (C. latifolia, and T. vulagris). Hematological indicators confirmed in vivo control of MRSA infection in all treatment groups except A. officinalis. This is first report confirming in vivo anti-MRSA potential of C. latifolia and T. vulgaris and highlight the need to explore bioactive constituents of these plants. Moreover, previously reported in vitro antibacterial efficiency of A. officinalis could not be validated in current study.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 19%
Student > Bachelor 5 16%
Researcher 4 13%
Student > Doctoral Student 2 6%
Lecturer 2 6%
Other 6 19%
Unknown 6 19%
Readers by discipline Count As %
Medicine and Dentistry 7 23%
Pharmacology, Toxicology and Pharmaceutical Science 5 16%
Immunology and Microbiology 4 13%
Agricultural and Biological Sciences 3 10%
Business, Management and Accounting 2 6%
Other 3 10%
Unknown 7 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2017.
All research outputs
#7,256,642
of 14,162,959 outputs
Outputs from BMC Complementary and Alternative Medicine
#983
of 2,938 outputs
Outputs of similar age
#153,998
of 400,452 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#89
of 408 outputs
Altmetric has tracked 14,162,959 research outputs across all sources so far. This one is in the 48th percentile – i.e., 48% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,938 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,452 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 408 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.