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The impact of a physician detailing and sampling program for generic atorvastatin: an interrupted time series analysis

Overview of attention for article published in Implementation Science, November 2017
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  • Above-average Attention Score compared to outputs of the same age (55th percentile)

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Title
The impact of a physician detailing and sampling program for generic atorvastatin: an interrupted time series analysis
Published in
Implementation Science, November 2017
DOI 10.1186/s13012-017-0671-z
Pubmed ID
Authors

Heather C. Worthington, Lucy Cheng, Sumit R. Majumdar, Steven G. Morgan, Colette B. Raymond, Stephen B. Soumerai, Michael R. Law

Abstract

In 2011, Manitoba implemented a province-wide program of physician detailing and free sampling for generic atorvastatin to increase use of this generic statin. We examined the impact of this unique combined program of detailing and sampling for generic atorvastatin on the use and cost of statin medicines, market share of generic atorvastatin, the choice of starting statin for new users, and switching from a branded statin to generic atorvastatin. We conducted a retrospective study of Manitoba insurance claims data for all continuously enrolled patients who filled one or more prescriptions for a statin between 2008 and 2013. Data were linked to physician-level data on the number of detailing visits and sample provision. We used interrupted time series analyses to assess policy-related changes in the use and cost of statin medicines, market share of generic atorvastatin, the choice of starting statin for new users, and switching from a branded statin to generic atorvastatin. The detailing program reached 31% (651/2103) of physicians who prescribed a statin during the study period. Collectively, these physicians prescribed 61% of statins dispensed in the province. Free sample cards were provided to 61% (394/651) of the detailed physicians. The program did not change the level or trend in the overall statin use rate and the total cost of statins or increase the number of patients switching from another branded statin to generic atorvastatin. We found the program had a small impact on atorvastatin's market share of new prescriptions, with a level increase of 2.6%. Though physician detailers were skilled at targeting high-prescribing physicians, a combined program of detailing visits and sample provision for generic atorvastatin did not lower overall statin costs or lead to switching from branded statins to the generic. The preceding introduction of generic atorvastatin appeared sufficient to modify prescribing patterns and decrease costs.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 21%
Researcher 4 17%
Student > Master 3 13%
Professor 3 13%
Lecturer 1 4%
Other 3 13%
Unknown 5 21%
Readers by discipline Count As %
Social Sciences 5 21%
Nursing and Health Professions 3 13%
Pharmacology, Toxicology and Pharmaceutical Science 3 13%
Medicine and Dentistry 2 8%
Business, Management and Accounting 1 4%
Other 4 17%
Unknown 6 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 November 2017.
All research outputs
#7,755,290
of 23,577,761 outputs
Outputs from Implementation Science
#1,251
of 1,728 outputs
Outputs of similar age
#151,769
of 441,117 outputs
Outputs of similar age from Implementation Science
#35
of 36 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,728 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.8. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 441,117 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.