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Novel antibiotic combinations proposed for treatment of Burkholderia cepacia complex infections

Overview of attention for article published in Antimicrobial Resistance & Infection Control, November 2017
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Title
Novel antibiotic combinations proposed for treatment of Burkholderia cepacia complex infections
Published in
Antimicrobial Resistance & Infection Control, November 2017
DOI 10.1186/s13756-017-0279-8
Pubmed ID
Authors

Omar M. El-Halfawy, Marwa M. Naguib, Miguel A. Valvano

Abstract

Effective strategies to manage Burkholderia cepacia complex (Bcc) infections in cystic fibrosis (CF) patients are lacking. We tested combinations of clinically available antibiotics and show that moxifloxacin-ceftazidime could inhibit 16 Bcc clinical isolates at physiologically achievable concentrations. Adding low dose of colistin improved the efficacy of the combo, especially at conditions mimicking CF respiratory secretions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 21%
Student > Ph. D. Student 6 14%
Researcher 5 12%
Student > Doctoral Student 3 7%
Other 3 7%
Other 6 14%
Unknown 11 26%
Readers by discipline Count As %
Medicine and Dentistry 11 26%
Immunology and Microbiology 8 19%
Biochemistry, Genetics and Molecular Biology 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Agricultural and Biological Sciences 3 7%
Other 3 7%
Unknown 11 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2018.
All research outputs
#15,150,745
of 25,732,188 outputs
Outputs from Antimicrobial Resistance & Infection Control
#879
of 1,477 outputs
Outputs of similar age
#227,402
of 448,354 outputs
Outputs of similar age from Antimicrobial Resistance & Infection Control
#23
of 32 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,477 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.7. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 448,354 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.