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Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

Overview of attention for article published in Genome Biology, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)

Mentioned by

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5 X users
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1 patent
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1 Facebook page

Citations

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200 Dimensions

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154 Mendeley
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1 CiteULike
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Title
Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
Published in
Genome Biology, December 2014
DOI 10.1186/s13059-014-0522-z
Pubmed ID
Authors

Elin Hall, Petr Volkov, Tasnim Dayeh, Jonathan Lou S Esguerra, Sofia Salö, Lena Eliasson, Tina Rönn, Karl Bacos, Charlotte Ling

Abstract

Epigenetic factors regulate tissue-specific expression and X-chromosome inactivation. Previous studies have identified epigenetic differences between sexes in some human tissues. However, it is unclear whether epigenetic modifications contribute to sex-specific differences in insulin secretion and metabolism. Here, we investigate the impact of sex on the genome-wide DNA methylation pattern in human pancreatic islets from 53 males and 34 females, and relate the methylome to changes in expression and insulin secretion.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 154 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 153 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 27%
Researcher 32 21%
Student > Bachelor 13 8%
Student > Master 13 8%
Student > Doctoral Student 7 5%
Other 13 8%
Unknown 34 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 49 32%
Agricultural and Biological Sciences 38 25%
Medicine and Dentistry 12 8%
Computer Science 5 3%
Neuroscience 3 2%
Other 7 5%
Unknown 40 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2022.
All research outputs
#6,275,484
of 25,371,288 outputs
Outputs from Genome Biology
#3,019
of 4,467 outputs
Outputs of similar age
#78,496
of 368,274 outputs
Outputs of similar age from Genome Biology
#74
of 101 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,274 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.