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Promoters from the itaconate cluster of Ustilago maydis are induced by nitrogen depletion

Overview of attention for article published in Fungal Biology and Biotechnology, November 2017
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  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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3 tweeters

Citations

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17 Dimensions

Readers on

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28 Mendeley
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Title
Promoters from the itaconate cluster of Ustilago maydis are induced by nitrogen depletion
Published in
Fungal Biology and Biotechnology, November 2017
DOI 10.1186/s40694-017-0040-3
Pubmed ID
Authors

Dominik Venc, Elena Geiser, Georg Wandrey, Hamed Hosseinpour Tehrani, Jochen Büchs, Lars M. Blank, Linda Büttner, Lisa M. Schmitz, Markus Schwarzländer, Melanie Beudels, Nick Wierckx, Sandra K. Hartmann, Thiemo Zambanini

Abstract

Ustilago maydis is known for its natural potential to produce a broad range of valuable chemicals, such as itaconate, from both industrial carbon waste streams and renewable biomass. Production of itaconate, and many other secondary metabolites, is induced by nitrogen limitation in U. maydis. The clustered genes responsible for itaconate production have recently been identified, enabling the development of new expression tools that are compatible with biotechnological processes. Here we report on the investigation of two of the native promoters, P tad1 and P mtt1 , from the itaconate cluster of U. maydis MB215. For both promoters the specific activation upon nitrogen limitation, which is known to be the trigger for itaconate production in Ustilago, could be demonstrated by gfp expression. The promoters cover a broad range of expression levels, especially when combined with the possibility to create single- and multicopy construct integration events. In addition, these reporter constructs enable a functional characterization of gene induction patterns associated with itaconate production. The promoters are well suited to induce gene expression in response to nitrogen limitation, coupled to the itaconate production phase, which contributes towards the further improvement of organic acid production with Ustilago.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 18%
Student > Doctoral Student 3 11%
Student > Master 3 11%
Researcher 3 11%
Student > Ph. D. Student 3 11%
Other 4 14%
Unknown 7 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 43%
Agricultural and Biological Sciences 5 18%
Engineering 2 7%
Chemical Engineering 1 4%
Unknown 8 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 November 2017.
All research outputs
#6,755,796
of 12,219,921 outputs
Outputs from Fungal Biology and Biotechnology
#34
of 54 outputs
Outputs of similar age
#148,238
of 339,498 outputs
Outputs of similar age from Fungal Biology and Biotechnology
#5
of 8 outputs
Altmetric has tracked 12,219,921 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 54 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,498 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.