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Oxidative stress and cellular pathologies in Parkinson’s disease

Overview of attention for article published in Molecular Brain, November 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#18 of 1,131)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
5 news outlets
twitter
4 X users
facebook
2 Facebook pages
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
347 Dimensions

Readers on

mendeley
472 Mendeley
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Title
Oxidative stress and cellular pathologies in Parkinson’s disease
Published in
Molecular Brain, November 2017
DOI 10.1186/s13041-017-0340-9
Pubmed ID
Authors

Lesly Puspita, Sun Young Chung, Jae-won Shim

Abstract

Parkinson's disease (PD) is a chronic and progressive neurodegeneration of dopamine neurons in the substantia nigra. The reason for the death of these neurons is unclear; however, studies have demonstrated the potential involvement of mitochondria, endoplasmic reticulum, α-synuclein or dopamine levels in contributing to cellular oxidative stress as well as PD symptoms. Even though those papers had separately described the individual roles of each element leading to neurodegeneration, recent publications suggest that neurodegeneration is the product of various cellular interactions. This review discusses the role of oxidative stress in mediating separate pathological events that together, ultimately result in cell death in PD. Understanding the multi-faceted relationships between these events, with oxidative stress as a common denominator underlying these processes, is needed for developing better therapeutic strategies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 472 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 472 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 66 14%
Student > Master 64 14%
Student > Ph. D. Student 61 13%
Researcher 40 8%
Student > Doctoral Student 35 7%
Other 51 11%
Unknown 155 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 79 17%
Neuroscience 64 14%
Pharmacology, Toxicology and Pharmaceutical Science 49 10%
Medicine and Dentistry 41 9%
Agricultural and Biological Sciences 27 6%
Other 40 8%
Unknown 172 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 47. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2022.
All research outputs
#768,793
of 23,164,913 outputs
Outputs from Molecular Brain
#18
of 1,131 outputs
Outputs of similar age
#19,106
of 439,294 outputs
Outputs of similar age from Molecular Brain
#1
of 14 outputs
Altmetric has tracked 23,164,913 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,131 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,294 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.