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Vitamin D and tuberculosis: a multicenter study in children

Overview of attention for article published in BMC Infectious Diseases, December 2014
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42 Dimensions

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102 Mendeley
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Title
Vitamin D and tuberculosis: a multicenter study in children
Published in
BMC Infectious Diseases, December 2014
DOI 10.1186/s12879-014-0652-7
Pubmed ID
Authors

Elisabetta Venturini, Ludovica Facchini, Nuria Martinez-Alier, Vas Novelli, Luisa Galli, Maurizio de Martino, Elena Chiappini

Abstract

BackgroundThe aim of this study is to evaluate vitamin D levels in children with latent and active TB compared to healthy controls of the same age and ethnical background.MethodsA multicenter observational study has been conducted in three tertiary care paediatric centres: Anna Meyer Children's University Hospital, Florence, Italy; Evelina London Children's Hospital, London, United Kingdom and Great Ormond Street Hospital, London, United Kingdom. Vitamin D was considered deficient if the serum level was <25 nmol/L, insufficient between 25 and 50 nmol/L and sufficient for a level >50 nmol/L.ResultsThe study population included 996 children screened for TB, which have been tested for vitamin D. Forty-four children (4.4%) had active TB, 138 (13.9%) latent TB and 814 (81.7%) were controls. Our study confirmed a high prevalence of hypovitaminosis D in the study population. A multivariate analysis confirmed an increased risk of hypovitaminosis D in children with latent and active TB compared to controls [(P¿=¿0.018; RR¿=¿1.61; 95%CI: 1.086-2.388), (P¿<¿0.0001; RR¿=¿4.587; 95%CI:1.190-9.608)].ConclusionsHypovitaminosis D was significantly associated with TB infection in our study. Further studies are needed to evaluate a possible role of vitamin D in the treatment and prevention of tuberculosis in children.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Tanzania, United Republic of 1 <1%
Unknown 101 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 22%
Student > Bachelor 13 13%
Student > Postgraduate 8 8%
Researcher 8 8%
Student > Ph. D. Student 7 7%
Other 15 15%
Unknown 29 28%
Readers by discipline Count As %
Medicine and Dentistry 40 39%
Nursing and Health Professions 9 9%
Agricultural and Biological Sciences 5 5%
Biochemistry, Genetics and Molecular Biology 5 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 10 10%
Unknown 31 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2018.
All research outputs
#14,792,181
of 22,774,233 outputs
Outputs from BMC Infectious Diseases
#4,067
of 7,668 outputs
Outputs of similar age
#203,028
of 361,188 outputs
Outputs of similar age from BMC Infectious Diseases
#94
of 194 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,668 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,188 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 194 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.