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Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53

Overview of attention for article published in Molecular Neurodegeneration, December 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

news
1 news outlet
twitter
3 X users
facebook
1 Facebook page

Citations

dimensions_citation
76 Dimensions

Readers on

mendeley
97 Mendeley
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Title
Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53
Published in
Molecular Neurodegeneration, December 2014
DOI 10.1186/1750-1326-9-56
Pubmed ID
Authors

Silvia Rossi, Caterina Motta, Valeria Studer, Giulia Macchiarulo, Elisabetta Volpe, Francesca Barbieri, Gabriella Ruocco, Fabio Buttari, Annamaria Finardi, Raffaele Mancino, Sagit Weiss, Luca Battistini, Gianvito Martino, Roberto Furlan, Jelena Drulovic, Diego Centonze

Abstract

Understanding how inflammation causes neuronal damage is of paramount importance in multiple sclerosis (MS) and in other neurodegenerative diseases. Here we addressed the role of the apoptotic cascade in the synaptic abnormalities and neuronal loss caused by the proinflammatory cytokines interleukin-1β (IL-1β) and tumor necrosis factor (TNF-α) in brain tissues, and disease progression caused by inflammation in relapsing-remitting MS (RRMS) patients.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 96 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 19%
Student > Ph. D. Student 15 15%
Researcher 9 9%
Other 8 8%
Student > Master 8 8%
Other 16 16%
Unknown 23 24%
Readers by discipline Count As %
Neuroscience 16 16%
Agricultural and Biological Sciences 13 13%
Medicine and Dentistry 13 13%
Biochemistry, Genetics and Molecular Biology 10 10%
Immunology and Microbiology 5 5%
Other 8 8%
Unknown 32 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2015.
All research outputs
#2,647,278
of 22,774,233 outputs
Outputs from Molecular Neurodegeneration
#341
of 847 outputs
Outputs of similar age
#38,873
of 356,557 outputs
Outputs of similar age from Molecular Neurodegeneration
#6
of 21 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 847 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,557 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.