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SMURF1 silencing diminishes a CD44-high cancer stem cell-like population in head and neck squamous cell carcinoma

Overview of attention for article published in Molecular Cancer, December 2014
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Title
SMURF1 silencing diminishes a CD44-high cancer stem cell-like population in head and neck squamous cell carcinoma
Published in
Molecular Cancer, December 2014
DOI 10.1186/1476-4598-13-260
Pubmed ID
Authors

Ali Khammanivong, Raj Gopalakrishnan, Erin B Dickerson

Abstract

Bone morphogenetic protein (BMP) signaling is thought to play key roles in regulating the survival and maintenance of cancer stem cells (CSCs), which contribute to disease recurrences and treatment failures in many malignances, including head and neck squamous cell carcinoma (HNSCC). Intracellular BMP signaling is regulated by SMAD specific E3 ubiquitin protein ligase 1 (SMURF1) during cellular development. However, little is known about the role or regulation of BMP signaling in HNSCC CSCs.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 22%
Researcher 5 19%
Other 3 11%
Student > Master 3 11%
Student > Ph. D. Student 3 11%
Other 3 11%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 9 33%
Biochemistry, Genetics and Molecular Biology 6 22%
Agricultural and Biological Sciences 6 22%
Computer Science 1 4%
Environmental Science 1 4%
Other 0 0%
Unknown 4 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2014.
All research outputs
#18,386,678
of 22,774,233 outputs
Outputs from Molecular Cancer
#1,288
of 1,719 outputs
Outputs of similar age
#261,383
of 360,902 outputs
Outputs of similar age from Molecular Cancer
#25
of 32 outputs
Altmetric has tracked 22,774,233 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,902 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.