Title |
In silico molecular cytogenetics: a bioinformatic approach to prioritization of candidate genes and copy number variations for basic and clinical genome research
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Published in |
Molecular Cytogenetics, December 2014
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DOI | 10.1186/s13039-014-0098-z |
Pubmed ID | |
Authors |
Ivan Y Iourov, Svetlana G Vorsanova, Yuri B Yurov |
Abstract |
The availability of multiple in silico tools for prioritizing genetic variants widens the possibilities for converting genomic data into biological knowledge. However, in molecular cytogenetics, bioinformatic analyses are generally limited to result visualization or database mining for finding similar cytogenetic data. Obviously, the potential of bioinformatics might go beyond these applications. On the other hand, the requirements for performing successful in silico analyses (i.e. deep knowledge of computer science, statistics etc.) can hinder the implementation of bioinformatics in clinical and basic molecular cytogenetic research. Here, we propose a bioinformatic approach to prioritization of genomic variations that is able to solve these problems. |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
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Brazil | 1 | 3% |
Unknown | 38 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 11 | 28% |
Student > Doctoral Student | 4 | 10% |
Researcher | 4 | 10% |
Student > Postgraduate | 4 | 10% |
Student > Master | 3 | 8% |
Other | 5 | 13% |
Unknown | 8 | 21% |
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Biochemistry, Genetics and Molecular Biology | 10 | 26% |
Medicine and Dentistry | 4 | 10% |
Computer Science | 3 | 8% |
Neuroscience | 2 | 5% |
Other | 2 | 5% |
Unknown | 6 | 15% |