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Chasing the precursor of functional hematopoietic stem cells at the single cell levels in mouse embryos

Overview of attention for article published in Journal of Hematology & Oncology, July 2016
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Title
Chasing the precursor of functional hematopoietic stem cells at the single cell levels in mouse embryos
Published in
Journal of Hematology & Oncology, July 2016
DOI 10.1186/s13045-016-0289-7
Pubmed ID
Authors

Xiaochen Wang, Yuemin Gong, Hideo Ema

Abstract

Adult hematopoietic stem cells (HSCs), the ideal system for regenerative research, were isolated at single cell levels decades ago, whereas studies on embryonic HSCs are much more difficult. Zhou et al identified a new pre-HSC cell surface marker, CD201, by which they isolated pre-HSCs at single cell levels for further analyses. The novel expression pattern of HSC development is revealed, including the fundamental role of mammalian targets of rapamycin (mTOR) signaling pathway in HSCs emergence, and the repopulation potential of S/G2/M phase pre-HSCs. Deeper understandings of the cellular origin and developmental regulatory network of HSCs are essential to develop new strategies of generating HSCs in vitro for clinical application.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 21%
Student > Bachelor 4 14%
Researcher 4 14%
Student > Master 3 11%
Professor 2 7%
Other 5 18%
Unknown 4 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 39%
Medicine and Dentistry 4 14%
Agricultural and Biological Sciences 2 7%
Immunology and Microbiology 2 7%
Unspecified 1 4%
Other 3 11%
Unknown 5 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2017.
All research outputs
#15,433,773
of 23,009,818 outputs
Outputs from Journal of Hematology & Oncology
#784
of 1,198 outputs
Outputs of similar age
#235,078
of 364,799 outputs
Outputs of similar age from Journal of Hematology & Oncology
#18
of 21 outputs
Altmetric has tracked 23,009,818 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,198 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 364,799 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.