Title |
Impact of missing participant data for dichotomous outcomes on pooled effect estimates in systematic reviews: a protocol for a methodological study
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Published in |
Systematic Reviews, November 2014
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DOI | 10.1186/2046-4053-3-137 |
Pubmed ID | |
Authors |
Elie A Akl, Lara A Kahale, Arnav Agarwal, Nada Al-Matari, Shanil Ebrahim, Paul Elias Alexander, Matthias Briel, Romina Brignardello-Petersen, Jason W Busse, Batoul Diab, Alfonso Iorio, Joey Kwong, Ling Li, Luciane Cruz Lopes, Reem Mustafa, Ignacio Neumann, Kari AO Tikkinen, Per Olav Vandvik, Yuqing Zhang, Pablo Alonso-Coello, Gordon Guyatt |
Abstract |
There is no consensus on how authors conducting meta-analysis should deal with trial participants with missing outcome data. The objectives of this study are to assess in Cochrane and non-Cochrane systematic reviews: (1) which categories of trial participants the systematic review authors consider as having missing participant data (MPD), (2) how trialists reported on participants with missing outcome data in trials, (3) whether systematic reviewer authors actually dealt with MPD in their meta-analyses of dichotomous outcomes consistently with their reported methods, and (4) the impact of different methods of dealing with MPD on pooled effect estimates in meta-analyses of dichotomous outcomes. |
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Mendeley readers
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