↓ Skip to main content

Homocysteine downregulates gene expression of heme oxygenase-1 in hepatocytes

Overview of attention for article published in Nutrition & Metabolism, December 2014
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
11 Dimensions

Readers on

mendeley
15 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Homocysteine downregulates gene expression of heme oxygenase-1 in hepatocytes
Published in
Nutrition & Metabolism, December 2014
DOI 10.1186/1743-7075-11-55
Pubmed ID
Authors

Xiaoqin Luo, Lei Xiao, Haixia Yang, Ruijuan Zhang, Manli Jiang, Jiahua Ni, Ting Lei, Nanping Wang

Abstract

Hyperhomocysteinemia (HHcy) is an independent risk factor for liver diseases, such as fatty liver and hepatic fibrosis. However, the mechanisms underlying this pro-oxidative effect of homocysteine (Hcy) in hepatocytes remain largely unknown. Thus, we investigated the effect of Hcy on the gene expression of heme oxygenase-1 (HO-1), the primary rate-limiting enzyme in heme catabolism and a key anti-oxidant detoxification enzyme in maintaining cellular redox homeostasis.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 2 13%
Researcher 2 13%
Other 2 13%
Student > Master 2 13%
Professor 2 13%
Other 4 27%
Unknown 1 7%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 27%
Pharmacology, Toxicology and Pharmaceutical Science 2 13%
Agricultural and Biological Sciences 2 13%
Unspecified 1 7%
Medicine and Dentistry 1 7%
Other 2 13%
Unknown 3 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2014.
All research outputs
#2,990,541
of 4,632,462 outputs
Outputs from Nutrition & Metabolism
#294
of 369 outputs
Outputs of similar age
#92,020
of 146,323 outputs
Outputs of similar age from Nutrition & Metabolism
#16
of 19 outputs
Altmetric has tracked 4,632,462 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 369 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 146,323 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.