Title |
L1CAM is expressed in triple-negative breast cancers and is inversely correlated with Androgen receptor
|
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Published in |
BMC Cancer, December 2014
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DOI | 10.1186/1471-2407-14-958 |
Pubmed ID | |
Authors |
Kai Doberstein, Karin Milde-Langosch, Niko P Bretz, Uwe Schirmer, Ayelet Harari, Isabell Witzel, Alon Ben-Arie, Michael Hubalek, Elisabeth Müller-Holzner, Susanne Reinold, Alain G Zeimet, Peter Altevogt, Mina Fogel |
Abstract |
Breast cancer is a heterogeneous disease displaying distinct molecular features and clinical outcome. The molecular profile of triple-negative breast cancers (TNBCs) overlaps with that of basal-like breast cancers that in turn show similarities with high-grade serous ovarian and endometrial carcinoma. L1CAM is an established biomarker for the latter cancers and we showed before that approximately 18% of primary breast cancers are positive for L1CAM and have a bad prognosis. Here we analysed the expression of L1CAM breast cancer subtypes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
France | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 39 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 26% |
Student > Master | 6 | 15% |
Student > Ph. D. Student | 6 | 15% |
Student > Bachelor | 5 | 13% |
Student > Doctoral Student | 3 | 8% |
Other | 5 | 13% |
Unknown | 4 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 23% |
Agricultural and Biological Sciences | 9 | 23% |
Biochemistry, Genetics and Molecular Biology | 7 | 18% |
Chemistry | 3 | 8% |
Business, Management and Accounting | 1 | 3% |
Other | 6 | 15% |
Unknown | 4 | 10% |